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Haladhar Dev Sarma Selected Research

Neoplasms (Cancer)

2/2024Evaluation of 177Lu-Labeled Pertuzumab F(ab')2 Fragments for HER2-Positive Cancer Targeting: A Comparative In Vitro and In Vivo Study.
6/2023Biochemical separation of Cetuximab-Fab from papain-digested antibody fragments and radiolabeling with 64Cu for potential use in radioimmunotheranostics.
3/2023[99mTc]Tc-HYNIC-RM2: A potential SPECT probe targeting GRPR expression in prostate cancers.
2/202368Ga-Labeled Trastuzumab Fragments for ImmunoPET Imaging of Human Epidermal Growth Factor Receptor 2 Expression in Solid Cancers.
1/2023Synthesis and 177Lu Labeling of the First Retro Analog of the HER2-Targeting A9 Peptide: A Superior Variant.
10/2022A solvent extraction-based procedure for removal of 46Sc impurity from reactor produced [45Ca]CaCl2 for its potential use in bone pain palliation.
9/2022Synthesis and comparative evaluation of 177Lu-labeled PEG and non-PEG variant peptides as HER2-targeting probes.
12/2020Reactor produced [64Cu]CuCl2 as a PET radiopharmaceutical for cancer imaging: from radiochemistry laboratory to nuclear medicine clinic.
3/202068 Ga-labeling of internalizing RGD (iRGD) peptide functionalized with DOTAGA and NODAGA chelators.
12/2019Preparation and clinical translation of 99mTc-PSMA-11 for SPECT imaging of prostate cancer.
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Haladhar Dev Sarma Research Topics

Disease

34Neoplasms (Cancer)
02/2024 - 04/2007
6Pain (Aches)
10/2022 - 12/2004
6Melanoma (Melanoma, Malignant)
12/2020 - 06/2014
5Fibrosarcoma
06/2023 - 01/2016
5Neoplasm Metastasis (Metastasis)
10/2022 - 09/2008
4Infections
11/2023 - 01/2017
4Prostatic Neoplasms (Prostate Cancer)
03/2023 - 04/2014
3Breast Neoplasms (Breast Cancer)
09/2022 - 11/2010
2Hyperthermia
01/2017 - 04/2007
2Arthritis (Polyarthritis)
06/2009 - 05/2006
1Bacterial Infections (Bacterial Infection)
11/2023
1Hypoxia (Hypoxemia)
05/2021
1Glioblastoma (Glioblastoma Multiforme)
12/2020
1Liver Neoplasms (Liver Cancer)
07/2020
1Non-Hodgkin Lymphoma (Lymphosarcoma)
10/2019
1Neuroendocrine Tumors (Neuroendocrine Tumor)
12/2017
1Hepatocellular Carcinoma (Hepatoma)
10/2010
1Inflammation (Inflammations)
06/2009

Drug/Important Bio-Agent (IBA)

7AcidsIBA
11/2023 - 12/2004
6Peptides (Polypeptides)IBA
03/2023 - 03/2017
51- (1,3- carboxypropyl)- 4,7- carboxymethyl- 1,4,7- triazacyclononaneIBA
11/2023 - 01/2017
4Radioisotopes (Radionuclides)IBA
10/2022 - 12/2004
3Pentetic Acid (DTPA)FDA LinkGeneric
02/2024 - 11/2014
3Chelating AgentsIBA
11/2023 - 07/2018
31,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidIBA
01/2023 - 11/2013
3RadiopharmaceuticalsIBA
12/2020 - 12/2004
3N,N'- bis(2- hydroxy- 5- (ethylene- beta- carboxy)benzyl)ethylenediamine N,N'-diacetic acidIBA
12/2019 - 03/2017
31,4,7- triazacyclononane- N,N',N''- triacetic acid (NOTA)IBA
10/2019 - 07/2018
3NGR peptideIBA
07/2019 - 01/2018
3Bevacizumab (Avastin)FDA Link
05/2017 - 11/2014
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
05/2017 - 11/2014
2human ERBB2 proteinIBA
02/2024 - 02/2023
2Trastuzumab (Herceptin)FDA Link
02/2024 - 02/2023
2ubiquicidin 31-38IBA
11/2023 - 07/2018
2Cetuximab (Erbitux)FDA Link
06/2023 - 01/2016
2Monoclonal AntibodiesIBA
06/2023 - 01/2016
2LigandsIBA
12/2019 - 01/2018
2IntegrinsIBA
10/2019 - 03/2017
2ribosomal protein S30IBA
07/2018 - 01/2017
2Folic Acid (Vitamin M)FDA LinkGeneric
01/2017 - 10/2016
2PorphyrinsIBA
11/2013 - 07/2010
1pertuzumabIBA
02/2024
1Antimicrobial PeptidesIBA
11/2023
1Immunoglobulin Fc FragmentsIBA
06/2023
1Immunoglobulin Fab FragmentsIBA
06/2023
1Bombesin Receptors (Bombesin Receptor)IBA
03/2023
1Therapeutic UsesIBA
02/2023
1Calcium-45IBA
10/2022
1SolventsIBA
10/2022
1azomycinIBA
05/2021
1NitroimidazolesIBA
05/2021
1cupric chloride (copper(II) chloride)FDA Link
12/2020
1gallium 68 PSMA-11IBA
12/2019
1arginyl-glycyl-aspartic acidIBA
10/2019
1Rituximab (Mabthera)FDA Link
10/2019
1cyclic arginine-glycine-aspartic acid peptideIBA
05/2019
1Arginine (L-Arginine)FDA Link
05/2019
1Aspartic Acid (Aspartate)FDA Link
05/2019
1Glycine (Aminoacetic Acid)FDA LinkGeneric
05/2019
11,4,7,10- tetraazacyclododecane- 1,4,7,10- tetrakis(methylenephosphonic acid) (DOTMP)IBA
01/2019
1Gallium-68IBA
07/2018
1glycyl-glycyl-glycine (triglycine)IBA
04/2018
1CarbonIBA
04/2018
1AmidesIBA
04/2018
1cyclo(aspargyl-glycyl-arginyl)IBA
01/2018
1SamariumIBA
01/2018
1samarium Sm-153 lexidronam (Quadramet)FDA Link
01/2018
1CD13 Antigens (Alanine Aminopeptidase)IBA
01/2018
1asparagine-glycine-arginineIBA
01/2018
1Somatostatin Receptors (Somatostatin Receptor)IBA
12/2017
1Erlotinib Hydrochloride (CP 358,774)FDA Link
10/2017
1Tyrosine Kinase InhibitorsIBA
10/2017
11,3,4,6-tetrachloro-3 alpha,6 alpha-diphenylglycolurilIBA
05/2017
1ethylenediamine (ethylenediamine dihydroiodide)FDA Link
03/2017
1ferric oxide (iron oxide)IBA
01/2017
1Dextrans (Dextran)FDA Link
01/2017
1Liposomes (Liposome)IBA
01/2017
1SuspensionsIBA
01/2017
1Paclitaxel (Taxol)FDA LinkGeneric
01/2017
1Octreotide (Sandostatin)FDA LinkGeneric
04/2015
1Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
04/2015
1perfluorosulfonic acid (Nafion)IBA
06/2014
1Progesterone Receptors (Progesterone Receptor)IBA
11/2010
1ProgesteroneFDA LinkGeneric
11/2010
1Oxyquinoline (8 Hydroxyquinoline)FDA Link
10/2010
1Ethiodized Oil (Ethiodol)FDA Link
10/2010
1Freund's AdjuvantIBA
06/2009
1177Lu- 1,4,7,10- tetraazacyclododecane- 1,4,7,10- tetrakis(methylenephosphonic acid)IBA
09/2008

Therapy/Procedure

6Therapeutics
06/2019 - 07/2010
3Precision Medicine
02/2024 - 01/2016
2Palliative Care (Palliative Therapy)
10/2022 - 02/2016
2Radiotherapy
07/2020 - 09/2008
2Intravenous Injections
07/2018 - 04/2007
2Radioimmunotherapy
05/2017 - 01/2016
2Brachytherapy
04/2014 - 08/2008
2Intra-Articular Injections
06/2009 - 05/2006
1Intravenous Administration
05/2019
1Nanospheres
04/2018
1Drug Therapy (Chemotherapy)
01/2017
1Gamma Cameras (Gamma Camera)
07/2010